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Use a sunscreen, wear protective clothing, and limit sun exposure while using this product and for a week afterwards. Active Ingredients: 7. Skin aging is a natural process, but daily sun exposure can contribute to premature aging.

Sun-damaged skin appears dull, with older, damaged cells accumulating due to slower skin cell turnover. See below for Important Safety Information. Tretinoin Gel 0. Tretinoin is for use on the skin only. Do not get it in your mouth, eyes, vagina or the corners of your nose. The safety and efficacy of Tretinoin have not been established in the treatment of patients younger than 10 years of age Gel or 12 years of age Cream , or in pregnant or nursing women. You are encouraged to report negative side effects of prescription drugs to the FDA. Visit www. Using the system helped Corinne reduce hyperpigmentation, uneven skin tone, and dark spots.

I was a little intimidated to have to use so many products and have to buy into some sort of system. I was skeptical. But all I can say is WOW! What a transformation. In only 2 weeks, most of my melasma has improved and the really tough spots I've had for years are noticeably faded!

Even the redness and peeling which I was warned ahead of time would happen were very manageable. I was floored! Again, thank you. The safety and effectiveness of the Nu-Derm System beyond 24 weeks of use have not been established. If no improvement is seen after 3 months of treatment, use of this product should be discontinued.

Join our exclusive program for helpful tips along the way to optimize your results. Looking for next steps after Obagi Nu-Derm? See how to maintain or continue your transformation for beautiful results. The safety of topical hydroquinone use during pregnancy or in children 12 years and under has not been established.

How to register a clinical trial in India? Sil A, Das NK - Indian J Dermatol

In case of accidental contact, patient should rinse eyes, nose, mouth, or lips with water and contact physician. Sunscreen use is an essential aspect of hydroquinone therapy because even minimal sunlight exposure sustains melanocytic activity. Contains sodium metabisulfite, a sulfite that may cause allergic-type reactions including anaphylactic symptoms and life-threatening or less severe asthmatic episodes in certain susceptible people.

Pregnancy Category C: Animal reproduction studies have not been conducted with topical hydroquinone. It is also not known whether hydroquinone can cause fetal harm when used topically on a pregnant woman or affect reproductive capacity. It is not known to what degree, if any, topical hydroquinone is absorbed systemically.

Topical hydroquinone should be used on pregnant women only when clearly indicated. Nursing Mothers: It is not known whether topical hydroquinone is absorbed or excreted in human milk. Caution is advised when topical hydroquinone is used by a nursing mother. Pediatric Usage: Safety and effectiveness in children below the age of 12 years have not been established.

Use of the product should be discontinued if hypersensitivity to any of the ingredients is noted. The safety and effectiveness beyond 24 weeks of use have not been established. Helps reduce visible signs of skin aging to help maintain younger looking skin. The safety and effectiveness beyond 12 weeks of use have not been established.

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Submission Preparation Checklist As part of the submission process, authors are required to check off their submission's compliance with all of the following items, and submissions may be returned to authors that do not adhere to these guidelines. The submission has not been previously published, nor is it before another journal for consideration or an explanation has been provided in Comments to the Editor.

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Where available, URLs for the references have been provided. The text is single-spaced; uses a point font; employs italics, rather than underlining except with URL addresses ; and all illustrations, figures, and tables are placed within the text at the appropriate points, rather than at the end. The text adheres to the stylistic and bibliographic requirements outlined in the Author Guidelines , which is found in About the Journal.

If submitting to a peer-reviewed section of the journal, the instructions in Ensuring a Blind Review have been followed. Draft the manuscript and critically revise the manuscript for any changes. Approve the final version of submission to the editorial board. Editorial policy All contributions are judged by the criteria of originality and scientific content, and preference will be given to original research articles.

The manuscripts submitted will be scrutinized by the editorial board and reviewed by independent experts. Double-blinded peer review process is followed. If accepted, the papers are subjected for editorial revision, including shortening of the text and omission of tables and figures if appropriate. Rapid review and publication is the policy of the journal. The editorial board reserves the right to reject the manuscript submitted for publication.

All articles should be accompanied by a covering letter bearing a statement to this effect signed by all authors. Dispute, if any, among the authors should be settled prior to the submission of the manuscript to the editorial board. Texts should be typed in Times New Roman font with font size of 12 point. Abbreviation should be written in full for the first time.

Title of the article Running title of the article Full names of each author, highest academic degree, their designations, affiliated institutional addresses, telephone numbers and email addresses Surname and initials of the first and middle names of each author should also be submitted. Complete address of the department and institution to which the work should be attributed Word count text only, exclusive of title, abstract, references, tables, and figure legends Number of figures, number of tables, number of references Statement of conflict of interest and sources of financial support Submission of manuscript: All manuscript should be submitted to the editor, NJDVL.

Le tt er to the editor The readers are invited to send comments, criticisms and questions related to specific article published in NJDVL Word limit — Maximum Number of references — 5 Review ar ti cles Reviews articles on the topics of interest in dermatology, sexually transmitted infection or leprosy. Priority will be given to those topics addressing a major current problem.

It should be critical and constructive analysis of the literatures related to the field of study. Preference will be given to articles of relevance to practice in developing nations.

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Should be short and accurate. Capitalize each word. Abstract Should not exceed words. No abbreviation should be used in abstract. Keywords Write words separated by semi colon in an alphabetical order at the end of the abstract. Word count — A brief introduction about the study should be provided, including: The rationale and objectives of the study. Concise background information to rationalize the study. The purpose of doing this study. Materials and Methods It should include sufficient information to permit other investigators to repeat the work.

It should include the following: Study type and design Duration and place of study Sample size Sampling technique Statistical methods and software used Inclusion and exclusion criteria Published procedure can be referred to by citation Include precise details of the questionnaires used, if any.

If the study was conducted on human subject, ethical consideration should be mentioned. Documented evidence granting such clearance should be attached to the manuscript. Results It should be presented in a logical sequence and supported by figures and tables, which should be essential to an understanding of the text.

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The same data should not be presented in the both tables and graphs. Discussion This emphasizes the newly and the important aspects of the study and conclusion that follow them. Do the repeat in detail data or material given in the introduction or result sections. The finding should be related to observation of other relevant studies.

It should include limitations of the study. Conclusion It should include a concise message, suggestion or recommendation as deducted from the content of the main manuscript. Acknowledgement It should be made at the end of the text before the references if any. References Should be in the Vancouver style of list. Authors are responsible for the accuracy of all references. In text, references are cited as superscript Arabic numerals, inserted before colons and semicolons and after comas and full stops without any spacing. While citing multiple references, use hyphen for a series of continuous numbers and comma for non-continuous numbers Examples — 1,2,3,4,5,8 can be written as ,8.

Reference list should be in numerical order and numbered consecutively as they appear in the text. It should not include unpublished items. Journal references The sequences for journal references should be: author s. Title of the paper are spelled out in full; all the main words have an initial capital letter. Abbreviated journal title. Year of publication; volume number issue number :page number Abbreviate page numbers Abbreviate months to first three letters, without full stop. Book references The sequence for the book references should be: author s. Chapter title; editors; book title; volume number; edition; place of publication; page number.